Viral Hepatitis Markers, Hepatotropic Viruses Summary updated: May 9, 2023 by Kamlesh kumar

 

Viral Hepatitis Markers, Hepatotropic Viruses Summary

 updated: May 9,  

Viral hepatitis Markers

Sample

  1. These tests are done in the serum of the patients.
  2. Various viral markers for the diagnosis of viral hepatitis.

Viral Hepatitis

Route of transmission

Antigen / Antibody

Appear (incubation period)

Antigen/Antibody Disappears

Virus structure

Stage of Disease

Hepatitis A

Feco-oral and sexual

HAV-IgM

4 to 6 weeks

3 to 4 months

27-nm RNA virus

Acute infection



HAV-IgA

8 to 12 weeks

10 years


Previous infection

Hepatitis B

Parenteral, sexual

HBsAg

4 to 12 weeks

1 to 3 months

42-nm DNA virus

Acute HBV infection



HBsAb

3 to 4 months

6 to 10 years


Immunity to HBV infection



HBeAg

1 to 3 weeks

6 to 8 weeks


Acute HBV infection



HBeAg

4 to 6 weeks

4 to 6 years


End of acute HBV infection



HBc IgM

2 to 12 weeks

3 to 6 months


Acute HBV infection



HBcAb-Total

3 to 12 months

for life


Recovery, or previous infection

Hepatitis C (HCV)

Parenteral, sexual

HCV-Ag

2 to 12 weeks

persists

30 to 60-nm RNA virus

Acute or chronic infection



HCV-IgG

3 to 4 months

2 years


past infection

Hepatitis D (HDV)

Feco-oral, sexual, and parenteral ?

HDV- Ag

1 to 3 days

3 to 5 days

36-nm RNA virus

Acute infection



HDV-IgM

10 days

1 to 3 months


Acute infection



HDV-Ab total

2 to 3 days

7 to 14 months


Chronic HDV infection

Hepatitis E (HEV)

Feco-oral

Anti-HEV

15 to 60 days


32-nm  RNA virus

Severe in pregnant females,



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